Greene et al., Biochim Biophys Acta 1999
:
These data implicate IRAK and TRAF-6 in transcriptional regulation of interleukin-2 gene expression via NFkappaB, and provide direct evidence that IRAK lies upstream from TRAF-6
Jensen et al., J Biol Chem 2001
(Carcinoma, Hepatocellular...) :
IRAK1b , a novel alternative splice variant of interleukin-1 receptor associated kinase ( IRAK ), mediates interleukin-1 signaling and has prolonged stability
Kim et al., J Biol Chem 2005
(Inflammation) :
Importantly, endogenous mPLK/IRAK was activated in response to TNF-alpha or interleukin 1 treatment of primary adipose cells