Gene interactions and pathways from curated databases and text-mining

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SREBF1 — THRSP

Text-mined interactions from Literome

Stoeckman et al., J Biol Chem 2002 : We found that SREBP-1c overexpression leads to a modest induction of fatty acid synthase, S(14) , and acetyl-CoA carboxylase mRNAs to 20 % ( fatty acid synthase ), 10 % ( S(14) ), and 5 % ( acetyl-CoA carboxylase ) of the induction seen by high glucose and insulin treatment
Wu et al., Hepatology 2013 (Disease Models, Animal...) : TO901317 treatment and LXR-a overexpression failed to induce, whereas overexpression of SREBP-1c significantly increased Thrsp promoter activity ... Moreover, deletion of the SRE site completely abolished SREBP-1c induced Thrsp transcription