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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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ANGPT2 — HRAS

Text-mined interactions from Literome

Gendron et al., Mol Endocrinol 1999 : Stimulation of NG108-15 cells with Ang II induced a decrease in GTP bound p21ras but a sustained increase in the activity of p42mapk and p44mapk as well as neurite outgrowth
Sadoshima et al., EMBO J 1996 : The p21 ras activation by Ang II is mediated by an increase in the guanine nucleotide exchange activity, but not by an inhibition of the GTPase activating protein
Eguchi et al., J Biol Chem 1996 : These data suggest that Ang II-induced MAPK activation through the Ang II type 1 receptor could be mediated by p21(ras)activation through a currently unidentified tyrosine kinase that lies downstream of Gq-coupled Ca2+/calmodulin signals
Li et al., EMBO J 1998 : In control cells, Ang II and TPA produced minimal increases in Ras-GTP level and Raf kinase activity ... In PKC depleted cells, Ang II increased Ras-GTP level and activated Raf and ERK in a Ras dependent manner
Jiao et al., Proc Natl Acad Sci U S A 1998 : The aim of this study was to determine whether arachidonic acid mediates Ang II 's effect on p21ras and if so, to ascertain the signaling mechanism ( s ) ... Moreover, Ang II and arachidonic acid induced an association between p21ras and Shc