Hara et al., J Exp Med 2004
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We report that Carma1 is essential for peptide induced interleukin 2 and interferon gamma production, but dispensable for proliferation in T cells
Lee et al., J Biol Chem 2010
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CARMA1 regulation of regulatory T cell development involves modulation of interleukin-2 receptor signaling ... We demonstrate that CARMA1 regulates IL-2 receptor signaling and controls the IL-2 stimulated maturation of Treg precursors to mature Tregs