Metheny-Barlow et al., Microvasc Res 2004
(Neovascularization, Pathologic) :
VEGF treatment of cultured smooth muscle cells ( SMC ) upregulated Tie2 and allowed for Ang1 mediated phosphorylation of Tie2 and the AKT serine-threonine kinase Jeong et al., Korean circulation journal 2010
:
Ang II increased LKB1 expression in a time dependent manner and peaked at an Ang II concentration of 10 ( -7 ) mole/L in VSMCs ... Ang II or balloon-injury increased the expression of LKB1 although the LKB1 activity was reduced ... Ang II increased LKB1 expression in VSMCs and neointima