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ICAM1 — SRC

Text-mined interactions from Literome

Chang et al., J Biol Chem 2002 : Tyrosine kinase inhibitors ( genistein or herbimycin ), Src family inhibitor ( PP2 ), or a phosphatidylinositol-phospholipase C inhibitor ( U73122 ) attenuated the IFN-gamma induced ICAM-1 expression
Huang et al., J Biol Chem 2003 : TNF-alpha- or 12-O-tetradecanoylphorbol-13-acetate ( TPA ) -induced ICAM-1 promoter activity was inhibited by a protein kinase C ( PKC ) inhibitor ( staurosporine ), tyrosine kinase inhibitors ( genistein and herbimycin A ), or an Src-specific tyrosine kinase inhibitor ( PP2 ) ... Furthermore, the dominant negative c-Src ( KM ) mutant inhibited induction of ICAM-1 promoter activity by TNF-alpha or TPA
Wang et al., J Biol Chem 2003 : Phenylarsine oxide, a tyrosine phosphatase inhibitor, reduced the base-line activity of SRC as well as the increase in SRC activity induced by ICAM-1 cross linking
Chang et al., Mol Pharmacol 2004 : Differential role of Janus family kinases ( JAKs ) in interferon-gamma induced lung epithelial ICAM-1 expression : involving protein interactions between JAKs, phospholipase Cgamma, c-Src , and STAT1 ... ICAM-1 promoter activities induced by the overexpression of wild-type JAK1- and PLC-gamma2 were blocked by the PLCgamma2 mutant or the dominant negative PKCalpha ( Lys -- > Arg ), c-Src ( Lys -- > Met ), or STAT1 ( Y701M ) mutants, but not by dominant negative STAT3 ( DN ) mutants
Amin et al., Blood 2006 : Antisense oligodeoxynucleotides ( ODNs ) and inhibitors of Src , PI3K, p38, and NFkappaB significantly reduced rhMIF induced MN VCAM-1 and ICAM-1 expression ( P < .05 )
Lin et al., J Cell Physiol 2007 (Lung Neoplasms) : We initially observed that IL-1beta induced ICAM-1 promoter activity was attenuated by the inhibitors of Src ( PP1 ), PDGFR ( AG1296 ), PI3-K ( LY294002 and wortmannin ), and Akt ( SH-5 ), revealed by reporter gene assay, Western blotting, and RT-PCR analyses ... The involvement of Src and PI3-K/Akt in IL-1beta induced ICAM-1 expression was significantly attenuated by transfection of A549 cells with dominant negative plasmids of Src, p85 and Akt, respectively
Yang et al., J Biol Chem 2010 (Mouth Neoplasms) : PGE ( 2 ) -induced expression of ICAM-1 and migration activity were inhibited by a specific inhibitor, siRNA, and mutants of PKCd, c-Src , and AP-1
Bernier et al., Molecular cancer 2011 (Breast Neoplasms...) : We then report that MUC1 forms constitutive cytoplasmic domain dimers which are necessary for Src recruitment, ICAM-1 induced calcium oscillations and simulated transendothelial migration ... We then report that MUC1 forms constitutive cytoplasmic domain dimers which are necessary for Src recruitment, ICAM-1 induced calcium oscillations and simulated transendothelial migration
Xie et al., Cell communication and signaling : CCS 2013 : Furthermore, overexpression of Cx43 or inhibition of c-Src attenuated the upregulation of intercellular adhesion molecule-1 ( ICAM-1 ), transforming growth factor-beta 1 ( TGF-ß1 ) and fibronectin ( FN ) expression induced by high glucose