Gene interactions and pathways from curated databases and text-mining

◀ Back to CDH1

CDH1 — SMAD2

Text-mined interactions from Literome

Medici et al., Mol Biol Cell 2006 : However, our results also demonstrate that a complete loss of E-cadherin and transformation to the mesenchymal phenotype are dependent on Smad signaling, which subsequently stimulates formation of beta-catenin/LEF-1 complexes that induce EMT
Kolosova et al., J Cell Physiol 2011 : However, neither Smad2/3 nor p38 MAPK were required for the down-regulation of E-cadherin , yet p38 MAPK was associated with fibronectin up-regulation
Liu et al., J Agric Food Chem 2012 (Carcinoma, Non-Small-Cell Lung...) : EGCG decreased the phosphorylation of Smad2 and Erk1/2, inhibited the nuclear translocation of Smad2 , and repressed the expression of transcription factors ZEB1, Snail, Slug, and Twist, and up-regulated the expression of E-cadherin