UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

NCI Pathway Database BMP receptor signaling: BMP2-4/BMPR2/BMPR1A-1B/RGM/XIAP complex (BMP4_BMP2-BMPR2-BMPR1A_BMPR1B-RGMB_RGMA_HFE2-XIAP) → TAK1/SMAD6 complex (MAP3K7-SMAD6) (modification, activates)
Kimura et al., J Biol Chem 2000, Yamaguchi et al., EMBO J 1999
Evidence: mutant phenotype, physical interaction
NCI Pathway Database BMP receptor signaling: BMP2-4/BMPR2/BMPR1A-1B/RGM/XIAP complex (BMP4_BMP2-BMPR2-BMPR1A_BMPR1B-RGMB_RGMA_HFE2-XIAP) → TAK1/TAB family complex (MAP3K7-TAB2_TAB1) (modification, activates)
Kimura et al., J Biol Chem 2000, Yamaguchi et al., EMBO J 1999
Evidence: mutant phenotype, physical interaction
NCI Pathway Database BMP receptor signaling: XIAP (XIAP) → BMP2-4/BMPR2/BMPR1A-1B/RGM/XIAP complex (BMP4_BMP2-BMPR2-BMPR1A_BMPR1B-RGMB_RGMA_HFE2-XIAP) (modification, collaborate)
Yamaguchi et al., EMBO J 1999
Evidence: physical interaction
NCI Pathway Database BMP receptor signaling: XIAP (XIAP) → BMP2-4/BMPR2/BMPR1A-1B/RGM complex (BMP4_BMP2-BMPR2-BMPR1A_BMPR1B-RGMB_RGMA_HFE2) (modification, collaborate)
Yamaguchi et al., EMBO J 1999
Evidence: physical interaction
NCI Pathway Database BMP receptor signaling: BMP2-4/BMPR2/BMPR1A-1B/RGM/XIAP complex (BMP4_BMP2-BMPR2-BMPR1A_BMPR1B-RGMB_RGMA_HFE2-XIAP) → BMP2-4/BMPR2/BMPR1A-1B/RGM complex (BMP4_BMP2-BMPR2-BMPR1A_BMPR1B-RGMB_RGMA_HFE2) (modification, collaborate)
Yamaguchi et al., EMBO J 1999
Evidence: physical interaction