Wehmeier et al., Biochim Biophys Acta 2005
(Liver Neoplasms) :
To assess the role of vitamin D receptor (VDR) in apo AI gene expression, we investigated the effect of 1alpha, 25-dihydroxycholecalciferol ( 1, 25- ( OH ) 2 D3 ) as well as the vitamin D antagonist ZK-191784 ( ZK ), on apo AI gene expression and promoter activity in the human hepatoma cell line HepG2
Wehmeier et al., Biochim Biophys Acta 2008
:
This induction did not require the VDR since antisense mediated inhibition of VDR had no appreciable effect on apo A-I promoter activity in cells treated with EB or ZK