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BCL2 — BDNF

Text-mined interactions from Literome

Schäbitz et al., Stroke 2000 (Brain Ischemia) : In this experiment we studied the effect of intravenous BDNF delivered after focal cerebral ischemia on neurological outcome, infarct size, and expression of proapoptotic and antiapoptotic proteins Bax and Bcl-2 , respectively
Lim et al., J Neurosci Res 2008 : Inhibition of ERKs inhibited the BDNF stimulated up-regulation of p35 and Bcl2
Kajiya et al., J Cell Physiol 2009 (Necrosis) : BDNF enhanced phosphorylated Akt levels, NF-kappaB activity in the nucleus, Bcl-2 mRNA levels, and mitochondrial membrane potential
Chao et al., Brain Pathol 2011 : Brain derived neurotrophic factor enhances Bcl-xL expression through protein kinase casein kinase 2-activated and nuclear factor kappa B-mediated pathway in rat hippocampus ... Moreover, transfection of CK2a small interfering RNA ( siRNA ) blocked the enhancing effect of BDNF on NF-?B phosphorylation and Bcl-xL expression ... Transfection of NF-?BS529A, the dominant negative mutant of NF-?B, prevented the enhancing effect of BDNF on Bcl-xL expression
Allsopp et al., Eur J Neurosci 1995 : Role of Bcl-2 in the brain derived neurotrophic factor survival response ... Our findings suggest that Bcl-2 is required for the BDNF survival response and that alternative, Bcl-2 independent survival mechanisms operate in sensory and parasympathetic neurons exposed to CNTF