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HSPB8 — IL6

Text-mined interactions from Literome

Wilhelmus et al., Neurobiol Aging 2009 (Cerebral Amyloid Angiopathy, Familial) : In addition, we demonstrated that Hsp20, HspB2 and HspB8 induced interleukin-6 production in cultured pericytes and astrocytes, which could be antagonized by dexamethasone, whereas other sHsps and A beta were inactive, suggesting that sHsps may be among the key mediators of the local inflammatory response associated with HCHWA-D and AD lesions
Roelofs et al., J Rheumatol 2008 (Arthritis, Rheumatoid) : In contrast, both LPS and HSPB8 resulted in significantly lower secretion of IL-6 , TNF-alpha, and IL-10 in those who carried the variant, whereas the frequency of CD14+ cells was higher in these individuals