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CD34 — IL6
Text-mined interactions from Literome
Drouet et al., Stem Cells 2001
:
We showed in a nonhuman primate model of autologous peripheral blood stem and progenitor cell transplantation that cell cycle activation of
CD34 ( + ) cells in the
presence of stem cell factor + FLT3-ligand + thrombopoietin
+ interleukin 3 ( six days of culture ) which induced G1 and S/G2/M cell amplification ( G0 : 6.1 % +/- 2.8 % ; G0/G1 : 64.2 % +/- 7.2 % ; S/G2/M : 30.4 % +/- 7.3 % respectively of expanded CD34 ( + ) cells on average ) resulted in the acceleration of short-term granulocyte recovery
Gupta et al., Blood 1998
:
Human
CD34 ( + ) bone marrow cells
regulate stromal production of
interleukin-6 and granulocyte colony stimulating factor and increase the colony stimulating activity of stroma