Gene interactions and pathways from curated databases and text-mining

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LTA — RHO

Text-mined interactions from Literome

Xing et al., J Appl Physiol 2011 (Acute Lung Injury...) : LTA and PepG markedly increased pulmonary EC permeability and activated p38 and ERK1/2 MAP kinases, NF-?B, and Rho/Rho kinase signaling
Seye et al., J Biol Chem 2012 : We show using RNAi techniques that knockdown of the actin binding protein filamin-A (FLNa) severely impaired nucleotide induced Rho activation and consequent Rho mediated LTA secretion
Wu et al., Translational research : the journal of laboratory and clinical medicine 2013 (Inflammation...) : In contrast, inhibition of p38 MAPK in microvascular ECs suppressed LTA/PepG induced activation of Rho , whereas the Rho inhibitor suppressed activation of p38 MAPK