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FLI1 — TP53

Text-mined interactions from Literome

Truong et al., Oncogene 2005 (Leukemia, Experimental...) : Since p53 protein expression levels are low, to undetectable, in primary erythroleukemic cells that express elevated levels of Fli-1, we investigated the potential regulation of p53 by Fli-1 ... We assessed whether the overexpression of Fli-1 could partially regulate p53 via modulation of its well established regulator, MDM2
Ban et al., Cancer Res 2008 (Sarcoma, Ewing) : Studying 6 ESFT cell lines, silencing of EWS-FLI1 in a wild-type p53 context resulted in increased p53 and p21 ( WAF1/CIP1 ) levels, causing cell cycle arrest