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MSK38 — RELA

Text-mined interactions from Literome

Olson et al., Infect Immun 2007 : The repression of MSK1 expression with small interfering RNA results in reduced RelA phosphorylation and a significant decrease in the production of TNF-alpha in response to B. burgdorferi lysates
Joo et al., J Biol Chem 2008 (Lung Neoplasms) : We further show that inhibition of MSK1 , a kinase acting downstream of MEK1/2-ERK1/2, by H89 or knockdown of MSK1 expression also inhibited phosphorylation of p65/RelA ( Ser ( 276 ) ), suggesting that this phosphorylation is dependent on MSK1 ... Our results indicate that the induction of inflammatory genes by farnesol is mediated by the activation of the NF-kappaB pathway and involves MEK1/2-ERK1/2-MSK1 dependent phosphorylation of p65/RelA ( Ser ( 276 ) )
László et al., Photochem Photobiol 2008 : Based upon our results, we propose a novel mechanism for translation regulated IkappaBalpha depletion and MSK mediated NF-kappaB activation at 24 h post-UV-irradiation
Reber et al., PloS one 2009 (Inflammation) : We show here that the MAPK downstream nuclear kinase MSK1 induces NF-kappaB p65 Ser276 phosphorylation upon IL-1beta treatment, which was inhibited in cells transfected with a MSK1 kinase-dead ( KD ) mutant compared to the WT control