◀ Back to TNF

APP — TNF

Text-mined interactions from Literome

Seguchi et al., Biol Chem 1999 (Adenocarcinoma...) : The extracellular accumulation of PN-II was also strongly stimulated either by interleukin-1beta (IL-1beta) treatment or to a lesser extent by basic fibroblast growth factor, tumor necrosis factor-alpha , hepatocyte growth factor or epidermal growth factor
Verbeek et al., J Histochem Cytochem 2002 : Both the cytokine interferon-gamma and the lysosomotropic drug chloroquine, but not the cytokines interleukin (IL)-1, IL-6, or tumor necrosis factor-alpha (TNF-alpha) , induced an accumulation of APP in newly formed multivesicular body-like organelles
Quadros et al., Neurosci Lett 2003 (Alzheimer Disease...) : In the present study, we used brain slices from transgenic APP Swedish ( TgAPPsw ) mice and control littermates of different age groups to determine the effect of APP overexpression on the levels of prostaglandin and tumor necrosis factor alpha (TNFalpha) release
Wright et al., J Cell Biochem 1992 : In cultures, GH, TNF-alpha and TGF-beta each inhibited lipid deposition, whereas TNF-alpha and TGF-beta, but not GH, inhibited AD-1 antigen expression
Sommer et al., J Cell Biochem 2009 : Interestingly, APP protein synthesis and mRNA expression were significantly increased by TNFalpha in a time dependent manner with maximal induction observed after 24 h of treatment ... Furthermore, TNFalpha induced APP mRNA expression dose-dependently with maximal 6.4-fold upregulation seen at 100 ng/ml effector ... Moreover, inhibitor experiments suggested that TNFalpha induced APP expression was mediated by nuclear factor kappa B. Taken together, we show for the first time a potent upregulation of APP by TNFalpha suggesting a potential role of this adipocyte secreted protein in TNFalpha induced insulin resistance and inflammatory disease
Antonioli et al., J Pharmacol Exp Ther 2010 (Body Weight...) : APP , EHNA, and dexamethasone counteracted the increments of spleen weight, ameliorated macroscopic and microscopic indexes of inflammation, and reduced TNF-a , IL-6, and MDA levels
Reiter et al., J Leukoc Biol 1994 : Neither ABPP nor tilorone induced TNF or IL-6
Libert et al., Eur J Immunol 1994 : We also observed that, in response to turpentine, TNF or IL-1, IL-6 ( 0/0 ) mice produced significantly less acute phase proteins (APP) than IL-6+/+ mice
Gabay et al., Clin Exp Immunol 1995 (Carcinoma, Hepatocellular) : Since previous studies on the contributions of cytokine inhibitors in connective tissues diseases suggested that IL-1 and tumour necrosis factor-alpha (TNF-alpha) might play an important role in the regulation of CRP, we decided to examine in more detail the respective roles of IL-1 beta, IL-6, and TNF-alpha and their inhibitors in the production of APP by human primary hepatocytes versus the hepatoma cell line PLC/PRF/5
Mackiewicz et al., Eur J Cell Biol 1993 (Carcinoma, Hepatocellular...) : So far, interleukin (IL) 6, transforming growth factor beta ( TGF beta ), tumor necrosis factor alpha (TNF) and IL-1 have been found to control N-glycosylation patterns of APP