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IL5 — PLA2G4A
Text-mined interactions from Literome
Urasaki et al., J Leukoc Biol 2001
:
In addition, AACOCF3, a selective
cPLA2 inhibitor, inhibited IL-5 induced CD69 expression on normal eosinophils, although it hardly
affected either
IL-5- or PAF induced CD69 expression on HES eosinophils ... These findings suggest that
IL-5 activates both
cPLA2 and 5-LO but PAF activates only 5-LO
Lefebvre et al., FASEB J 2010
:
As negative controls,
interleukin-8- and formyl-methionyl-leucyl-phenylalanine elicited migration in vitro was not
inhibited either by an LTB ( 4 ) receptor antagonist or by the
cPLA(2)alpha inhibitor
Chi et al., Arthritis Rheum 2011
(Arthritis, Rheumatoid) :
Cytosolic phospholipase A2 induction and prostaglandin E2 release by
interleukin-1ß via the myeloid differentiation factor 88-dependent pathway and cooperation of p300, Akt, and NF-?B activity in human rheumatoid arthritis synovial fibroblasts