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CCL20 — IL1B
Text-mined interactions from Literome
Matsui et al., Clin Exp Immunol 2001
(Arthritis, Rheumatoid) :
Cultured synovial fibroblasts derived from either RA or OA patients were capable of producing
MIP-3 alpha in
response to
IL-1 beta and TNFalpha in vitro
Cardozo et al., Diabetologia 2003
:
The expression of IL-15, IP-10 and fractalkine is regulated by IFN-gamma, while the expression of
MIP-3alpha is
IL-1beta dependent
Ruth et al., Lab Invest 2003
(Arthritis, Rheumatoid...) :
IL-1beta , IL-18, and TNF-alpha
stimulated RA fibroblast
MIP-3alpha production at 48 hours of incubation in vitro
Starner et al., Am J Respir Cell Mol Biol 2003
:
Expression of
CCL20 transcripts were significantly
induced by interleukin
(IL)-1beta and tumor necrosis factor-alpha, and inhibited by dexamethasone ... Primary cultures of airway epithelia secreted
CCL20 both apically and basolaterally, and CCL20 abundance was
increased over 30-fold with
IL-1beta stimulation, achieving an estimated concentration of 167 ng/ml in airway surface liquid
Veckman et al., J Leukoc Biol 2003
:
CCL19 and
CCL20 mRNA expression was
up-regulated by
IL-1beta or tumor necrosis factor alpha (TNF-alpha), and in addition, IFN-alpha together with TNF-alpha further enhanced CCL19 gene expression
Hosokawa et al., Clin Exp Immunol 2005
:
Here, we report that
interleukin-1 beta (IL-1beta) , tumour necrosis factor-alpha (TNF-alpha) and Escherichia coli lipopolysaccharide (LPS) can significantly
induce the production of
CCL20 by HGF ... In contrast, interferon-gamma (IFN-gamma) dramatically diminished
CCL20 production
induced by
IL-1beta ... Moreover, we demonstrated that nuclear factor-kappaB (NF-kappaB), p38 mitogen activated protein kinase ( MAPK ) and extracellular signal regulated kinases ( ERK ) play an important role in mediating the production of
CCL20 induced by
IL-1beta and TNF-alpha
Lee et al., Inflamm Bowel Dis 2005
(Colitis, Ulcerative) :
Moreover, tumor necrosis factor-alpha- or
interleukin-1beta induced
CCL20 secretion was greatly diminished by 5-aminosalicylic acid and/or glucocorticoid treatment of human intestinal epithelial HT-29 cells
Hirota et al., J Exp Med 2007
(Arthritis, Experimental...) :
The
CCL20 production by synoviocytes is
augmented in vitro by
IL-1beta , IL-17, or tumor necrosis factor alpha, and is suppressed by IFN-gamma or IL-4
Sandell et al., Osteoarthritis Cartilage 2008
(Arthritis) :
In the
presence of
IL-1beta , FGF-18 increased expression of ADAMTS-4, aggrecan, BMP-2, COL2A1, CCL3, CCL4,
CCL20 , CXCL1, CXCL3, CXCL6, IL-1beta, IL-6, and IL-8 and decreased ADAMTS-5, MMP-13, CCL2, and CCL8
Terao et al., Neurosci Res 2009
(Hypothermia...) :
In turn,
MIP-3alpha stimulated
IL-1beta and inducible nitric oxide synthase expressions in rat microglia and rat brains
Tanida et al., Cytokine 2009
(Arthritis, Rheumatoid) :
IL-1beta vigorously
induced the production of
CCL20 from FLSs of human RA and the production of CCL20 induced by TNF-alpha was partially attributed to a trace amount of IL-1beta induced by TNF-alpha ... The production of
CCL20 induced by TNF-alpha and
IL-1beta was modified by helper-T-cell derived cytokines
Kawashiri et al., J Rheumatol 2009
(Arthritis, Rheumatoid) :
In contrast, interferon-gamma suppressed
IL-1beta induced
CCL20 production