Gene interactions and pathways from curated databases and text-mining

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CCL20 — IL1B

Text-mined interactions from Literome

Matsui et al., Clin Exp Immunol 2001 (Arthritis, Rheumatoid) : Cultured synovial fibroblasts derived from either RA or OA patients were capable of producing MIP-3 alpha in response to IL-1 beta and TNFalpha in vitro
Cardozo et al., Diabetologia 2003 : The expression of IL-15, IP-10 and fractalkine is regulated by IFN-gamma, while the expression of MIP-3alpha is IL-1beta dependent
Ruth et al., Lab Invest 2003 (Arthritis, Rheumatoid...) : IL-1beta , IL-18, and TNF-alpha stimulated RA fibroblast MIP-3alpha production at 48 hours of incubation in vitro
Starner et al., Am J Respir Cell Mol Biol 2003 : Expression of CCL20 transcripts were significantly induced by interleukin (IL)-1beta and tumor necrosis factor-alpha, and inhibited by dexamethasone ... Primary cultures of airway epithelia secreted CCL20 both apically and basolaterally, and CCL20 abundance was increased over 30-fold with IL-1beta stimulation, achieving an estimated concentration of 167 ng/ml in airway surface liquid
Veckman et al., J Leukoc Biol 2003 : CCL19 and CCL20 mRNA expression was up-regulated by IL-1beta or tumor necrosis factor alpha (TNF-alpha), and in addition, IFN-alpha together with TNF-alpha further enhanced CCL19 gene expression
Hosokawa et al., Clin Exp Immunol 2005 : Here, we report that interleukin-1 beta (IL-1beta) , tumour necrosis factor-alpha (TNF-alpha) and Escherichia coli lipopolysaccharide (LPS) can significantly induce the production of CCL20 by HGF ... In contrast, interferon-gamma (IFN-gamma) dramatically diminished CCL20 production induced by IL-1beta ... Moreover, we demonstrated that nuclear factor-kappaB (NF-kappaB), p38 mitogen activated protein kinase ( MAPK ) and extracellular signal regulated kinases ( ERK ) play an important role in mediating the production of CCL20 induced by IL-1beta and TNF-alpha
Lee et al., Inflamm Bowel Dis 2005 (Colitis, Ulcerative) : Moreover, tumor necrosis factor-alpha- or interleukin-1beta induced CCL20 secretion was greatly diminished by 5-aminosalicylic acid and/or glucocorticoid treatment of human intestinal epithelial HT-29 cells
Hirota et al., J Exp Med 2007 (Arthritis, Experimental...) : The CCL20 production by synoviocytes is augmented in vitro by IL-1beta , IL-17, or tumor necrosis factor alpha, and is suppressed by IFN-gamma or IL-4
Sandell et al., Osteoarthritis Cartilage 2008 (Arthritis) : In the presence of IL-1beta , FGF-18 increased expression of ADAMTS-4, aggrecan, BMP-2, COL2A1, CCL3, CCL4, CCL20 , CXCL1, CXCL3, CXCL6, IL-1beta, IL-6, and IL-8 and decreased ADAMTS-5, MMP-13, CCL2, and CCL8
Terao et al., Neurosci Res 2009 (Hypothermia...) : In turn, MIP-3alpha stimulated IL-1beta and inducible nitric oxide synthase expressions in rat microglia and rat brains
Tanida et al., Cytokine 2009 (Arthritis, Rheumatoid) : IL-1beta vigorously induced the production of CCL20 from FLSs of human RA and the production of CCL20 induced by TNF-alpha was partially attributed to a trace amount of IL-1beta induced by TNF-alpha ... The production of CCL20 induced by TNF-alpha and IL-1beta was modified by helper-T-cell derived cytokines
Kawashiri et al., J Rheumatol 2009 (Arthritis, Rheumatoid) : In contrast, interferon-gamma suppressed IL-1beta induced CCL20 production