Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Motta et al., Mol Cell Endocrinol 2007 : Inactivating the function of STAT-3 by expression of a short hairpin RNA demonstrated that the effect of leptin on beta-casein expression is mediated by STAT-3
Feuermann et al., J Endocrinol 2006 : Leptin antagonist abolished the effect of leptin on alpha-casein expression in mammary gland explants when exogenous leptin was not present in the medium
Lin et al., Sci China C Life Sci 2007 (MAP Kinase Signaling System) : In lactation, leptin induced gene expression of beta-casein by JAK-STAT5 signal pathway, and in involution leptin induced mammary epithelial cell apoptosis and mammary gland restitution by JAK-STAT3 signal pathway