◀ Back to ITGB1

AKT2 — ITGB1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: ITGB1 → AKT2 (increases) Arboleda et al., Cancer Res 2003*
  Evidence: AKT2 transfectants demonstrated increased adhesion and invasion through collagen IV because of up-regulation of beta1 integrins (ITGB1)
• OpenBEL Selventa BEL large corpus: ITGB1 → AKT2 (increases)
  Evidence: Overexpression of AKT2 was shown to upregulate b1 integrins and increase invasiveness/metastasis in human breast and ovarian cancer cells

Text-mined interactions from Literome

Redondo-Muñoz et al., Blood 2006 (Leukemia, B-Cell...) : This effect was mediated by alpha4beta1 integrin and required PI3-K/Akt signaling
Loufrani et al., Am J Physiol Heart Circ Physiol 2008 (Mechanotransduction, Cellular) : Key role of alpha(1)beta(1)-integrin in the activation of PI3-kinase-Akt by flow ( shear stress ) in resistance arteries