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IL8 — S100A12

Text-mined interactions from Literome

Raap et al., J Rheumatol 2000 (Arthritis, Rheumatoid...) : In RA fibroblasts, CGRP increased IL-6 and IL-8 secretion at 10 ( -10 ) to 10 ( -8 ) M ( p at least < 0.01 ), which was not observed in OA fibroblasts
Tan et al., Sheng Li Xue Bao 2002 : The results of the experiments showed that VIP exerted an inhibitory effect on the secretion of IL-1 and IL-8 from unstimulated and O3-stressed BECs, VIP also decreased the secretion of IL-5 from O3-stressed BECs ; EGF promoted secretion of IL-1 and IL-8 from unstimulated BECs, but decreased the secretion of ILs from O3-stressed BECs ; ET-1 and CGRP enhanced the secretion of IL-1, IL-5, and IL-8 from unstimlated BECs, CGRP also increased the secretion of ILs from O3-stressed BECs
Patel et al., Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003 (Neurogenic Inflammation) : IL-8 secretion from pulp cells increased significantly at 10 ( -8 ) to 10 ( -4 ) mol/L of SP stimulation ( 5- to 13.8-fold ; P < .05 ) ; however, no significant IL-8 increase with CGRP ( up to 10 ( -4 ) mol/L ) stimulation was observed, nor was there synergistic induction of IL-8 with SP plus CGRP ... SP at a concentration of 10 ( -4 ) mol/L created minimal IL-8 induction in the endothelial cells and no synergistic induction by SP and CGRP
Park et al., Int Endod J 2004 (Neurogenic Inflammation...) : CGRP did not induce IL-8 , but moderately increased MCP-1 production ( approximately three fold ) in cultured pulp cells
Dallos et al., Neuropeptides 2006 (Inflammation) : The aims of this study were a systematic investigation of the effects of the neuropeptides substance P ( SP ), calcitonin gene related peptide (CGRP) , vasoactive intestinal polypeptide (VIP) and galanin (GAL) on the inflammatory cytokine production ( IL-1alpha, IL-8 and TNF-alpha ) of the keratinocytes, and a study of their role in the production and secretion of nerve growth factor (NGF) and its precursor molecule ( proNGF )
Li et al., Acta Pharmacol Sin 2006 (Lung Neoplasms) : In the present study, we investigated the effect of endogenous and exogenous CGRP on IL-1beta induced chemokine interleukin-8 (IL-8) secretion ... The inhibition of CGRP expression by siRNA significantly increased IL-8 secretion upon IL-1beta stimulation
Abbas et al., Stroke 2012 (Carotid Artery Diseases...) : Our main findings were : ( 1 ) plasma levels of S100A12 were significantly higher in patients with carotid atherosclerosis compared with healthy control subjects with the highest levels in patients with the most recent symptoms ( ie, within 2 months ) ; ( 2 ) plasma levels of S100A8/S100A9 showed a modest increase in patients with symptoms in the previous 2 to 6 months but not in the other patients ; ( 3 ) mRNA levels of S100A8, S100A9, and S100A12 showed increased expression in atherosclerotic carotid plaques from patients with the most recent symptoms compared with the remaining patients ; ( 4 ) in THP-1 monocytes, activation of Toll-like receptors 2 and 4 increased mRNA levels of S100A8, S100A9, and S10012 and interleukin-1ß , interferon ?, and releasate from thrombin activated platelets significantly enhanced the expression of S100A12
Chung et al., PloS one 2013 (Inflammation) : S100A12 did not stimulate IL-6, IL-8 , IL-1ß or TNF-a production by human peripheral blood mononuclear cells but low amounts consistently reduced cytokine mRNA and protein levels induced by serum amyloid A, by ~49 % and ~46 %, respectively