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EGF — GAB2

Text-mined interactions from Literome

Kong et al., Mol Endocrinol 2003 : More recently, we found that EGF dependent tyrosine phosphorylation of endogenous Gab2 is essential for EGF induced DNA synthesis in rat hepatocytes ... Western blotting of subcellular fractions from intact liver and immunofluorescence analyses in cultured hepatocytes demonstrated that EGF did not promote the association of cytosolic Gab2 with cell membranes ... Overexpression of the PH domain of Gab2 did not affect EGF induced Gab2 phosphorylation, PI3K activation, and DNA synthesis
Meng et al., Biochem J 2005 (MAP Kinase Signaling System) : Participation of both Gab1 and Gab2 in the activation of the ERK/MAPK pathway by epidermal growth factor