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IGF1 — SHH

Text-mined interactions from Literome

Nakamura et al., PloS one 2010 (Carcinoma, Pancreatic Ductal...) : In vitro co-culture and matrigel plug assays demonstrated that PDAC cell derived Shh induced Ang-1 and IGF-1 production in BMPCs, resulting in their enhanced migration and capillary morphogenesis activity
Fernandez et al., Dev Neurosci 2010 : Whereas the proliferative activity of IGF1 or IGF2 on GCPs does not require intact SHH signaling, aspects of SHH activity on GCP proliferation require signaling through the IGF receptor 1