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PPARG — PTBP2

Text-mined interactions from Literome

Hammad et al., Am J Pathol 2004 (Asthma...) : In the present report, we investigated the possibility that, by targeting DCs , PPAR-gamma activation may be involved in the regulation of the pulmonary immune response to allergens
Appel et al., Blood 2005 : Activation of PPAR-gamma resulted in a reduced stimulation of DCs via the TLR ligands 2, 3, 4, and 7, characterized by down-regulation of costimulatory and adhesion molecules and reduced secretion of cytokines and chemokines involved in T-lymphocyte activation and recruitment
Szatmari et al., Blood 2007 : Our data show that PPARgamma acts as a mostly positive transcriptional regulator in human developing DCs , acting primarily through controlling genes involved in lipid metabolism and via this, indirectly modifying the immune phenotype