◀ Back to AKT1
AKT1 — EEF1A2
Text-mined interactions from Literome
Brouet et al., Circ Res 2001
:
Finally, we showed that
statin promoted the tyrosine phosphorylation of hsp90 and the direct interaction of hsp90 with
Akt , which further potentiated the NO-dependent angiogenic processes
Skaletz-Rorowski et al., Cardiovasc Res 2003
(Translocation, Genetic) :
Treatment with phosphoinositide 3-kinase ( PI 3-kinase ) inhibitors or the HMG-CoA reductase reaction product L-mevalonate blocks the translocation of
Akt in
response to
statin stimulation ... These results suggest that
statin activation of
Akt signaling is mediated by the translocation of Akt to cholesterol-sensitive membrane structures within activated ECs
Cosentino et al., Recenti Prog Med 2003
(Acute Disease...) :
Recent findings on
statin induced inhibition of Rho/Rho-kinase and
activation of
Akt provide new insights into the protective action of statins in acute coronary syndromes
Bussolati et al., J Am Soc Nephrol 2005
:
The
statin induced
Akt activation may protect from the loss of nephrin by an inhibition of its redistribution and shedding and by a stimulation of its synthesis
Roudier et al., Mol Cancer Ther 2006
(Carcinoma, Hepatocellular...) :
Taken together, these data suggest that a mTOR
dependent ,
statin induced inhibition of
Akt phosphorylation and nuclear translocation sensitizes cells to cytostatic drugs
Amiri et al., Oncogene 2007
(Breast Neoplasms...) :
eEF1A2 activates
Akt and stimulates Akt dependent actin remodeling, invasion and migration ... Furthermore,
eEF1A2 expression is sufficient to activate Akt in a PI3K dependent fashion and inactivation of eEF1A2 by short interfering RNA
reduces Akt activity
Merla et al., Am J Physiol Heart Circ Physiol 2007
:
The central role of adenosine in
statin induced ERK1/2,
Akt , and eNOS phosphorylation