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ANG — BAX
Text-mined interactions from Literome
Bhaskaran et al., American journal of physiology. Renal physiology 2003
:
In addition,
ANG II
increased RPTEC expression of
Bax , a cell death protein
Paudel et al., J Virol 2012
:
Silencing
ANG or inhibiting its nuclear translocation
resulted in decreased nuclear LANA-1 and ANG levels, decreased interactions between ANG-LANA-1, ANG-p53, and LANA-1-p53, the induction of p53, p21, and
Bax proteins, the increased cytoplasmic localization of p53, the downregulation of Bcl-2, the increased cleavage of caspase-3, and the apoptosis of cells
Jiang et al., Pharmacol Res 2013
(Hypertension) :
The increases of the percentage of TUNEL positive neurons and
Bax to Bcl-2 ratio in SHR brain were also
attenuated by
Ang- ( 1-7 )