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IL8 — PLD1
Text-mined interactions from Literome
Atta-ur-Rahman et al., Curr Pharm Des 1999
(Inflammation) :
Neutrophils activation of
phospholipase D ( PLD ) and superoxide generation in
response to
IL-8 have also been demonstrated
Conquer et al., Osteoarthritis Cartilage 1994
:
Effect of
interleukin 1, lipopolysaccharide and phorbol esters on
phospholipase D activity in chondrocytes
Wang et al., Biochem J 2002
:
The
roles of
PLD1 and PLD2 in ERK activation and
IL-8 secretion activated by S1P were investigated by infecting cells with adenoviral constructs of wild-type and catalytically inactive mutants of PLD1 and PLD2
Grab et al., Biochim Biophys Acta 2004
:
Differential
role for
phospholipase D1 and phospholipase D2 in 12-O-tetradecanoyl-13-phorbol acetate stimulated MAPK activation, Cox-2 and
IL-8 expression ... We used this system to differentiate the
effect of
PLD1 or PLD2 activity on the expression of Cox-2 and
IL-8
Bacon et al., J Immunol 1995
:
By contrast, this
IL-8 dependent
PLD activity was undetectable in IL-8 stimulated neutrophils
L'Heureux et al., Blood 1995
:
Diverging signal transduction pathways activated by interleukin-8 and related chemokines in human neutrophils
: interleukin-8 , but not NAP-2 or GRO alpha,
stimulates phospholipase D activity ... The ability of
IL-8 to
stimulate the activity of
PLD was additively enhanced, or primed, by cytochalasin B and by tumor necrosis factor alpha
Sozzani et al., Blood 1994
:
Activation of
phospholipase D by
interleukin-8 in human neutrophils