Disse et al., Blood 2009
:
Phospholipase D1 is specifically required for regulated secretion of von Willebrand factor from endothelial cells
Huang et al., Blood 2012
:
Another PLD1 activator, ADP-ribosylation factor 6, was involved in VWF secretion induced by Stx1B or Stx2B, but not histamine ... These data indicate that Stx1B and Stx2B induce acute VWF secretion in a PLD1 dependent manner but do so by differentially modulating PKCa, RhoA, and ADP-ribosylation factor 6