Gene interactions and pathways from curated databases and text-mining

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IL10 — REL

Text-mined interactions from Literome

Grumont et al., J Exp Med 2001 : c-Rel regulates interleukin 12 p70 expression in CD8 ( + ) dendritic cells by specifically inducing p35 gene transcription
Temmerman et al., Blood 2006 (Ectodermal Dysplasia...) : As a consequence, CD40 stimulated EDI DCs failed to synthesize the c-Rel dependent cytokine interleukin-12 , had impaired up-regulation of costimulatory molecules, and failed to support allogeneic lymphocyte proliferation in vitro
Romano et al., J Immunol 1996 : IL-10 inhibits nuclear factor-kappa B/Rel nuclear activity in CD3 stimulated human peripheral T lymphocytes ... IL-10 markedly reduces nuclear factor (NF)-kappa B/Rel nuclear activity induced in PBMC by stimulation with the anti-CD3 mAb OKT3 ... Our results demonstrate that IL-10 can inhibit the induction of NF-kappa B/Rel nuclear activity in CD3 stimulated T lymphocytes