Gene interactions and pathways from curated databases and text-mining

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CD46 — IL15

Text-mined interactions from Literome

d'Ettorre et al., AIDS 2002 (HIV Infections) : The following parameters were evaluated : the production of IL-15 by peripheral blood mononuclear cells ( PBMC ) stimulated with lipopolysaccharide, Candida albicans and Mycobacterium avium complex ; the ability of IL-15 to induce the secretion of IL-8 and monocyte chemotactic protein-1 (MCP-1) from HIV positive monocytes ; and the virological effect of IL-15 and IL-2 on HIV replication in mononuclear cells
Marie et al., Nat Immunol 2002 (Dermatitis, Contact...) : We found that engagement of CD46-1 or CD46-2 differentially affected CD8 ( + ) T cell cytotoxicity, CD4 ( + ) T cell proliferation, interleukin 2 (IL-2) and IL-10 production as well as tyrosine phosphorylation of Vav in T lymphocytes