UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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AFP — CASP10

Text-mined interactions from Literome

Semenkova et al., Eur J Biochem 2003 : Alpha-fetoprotein positively regulates cytochrome c-mediated caspase activation and apoptosome complex formation
Li et al., Int J Cancer 2009 (Carcinoma, Hepatocellular...) : In the current study, we investigated the role of the cytoplasmic AFP in caspase-3 mediated signaling of apoptosis ... The effect of AFP on caspase-3 was further confirmed by transfection of the AFP gene into HLE cells ( AFP negative )