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CD40 — MAP3K14
Text-mined interactions from Literome
Mukundan et al., J Immunol 2005
:
However, ligation of a CD40 mutant lacking a functional TRAF6 binding site did not initiate inflammatory cytokine production, and this mutant was found to be defective in
CD40 mediated
activation of ERK1/2, as well as
IkappaB kinase (IKK) and NF-kappaB
Chan et al., Biochem Biophys Res Commun 2005
:
Tpl2/COT1 was shown to participate in CD40 signaling based on the ability of a catalytically inactive mutant to suppress
CD40 mediated
IkappaB kinase activation and induction of NFkappaB-responsive promoters, without affecting signaling by TNF