Gene interactions and pathways from curated databases and text-mining

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CD40 — MAP3K14

Text-mined interactions from Literome

Mukundan et al., J Immunol 2005 : However, ligation of a CD40 mutant lacking a functional TRAF6 binding site did not initiate inflammatory cytokine production, and this mutant was found to be defective in CD40 mediated activation of ERK1/2, as well as IkappaB kinase (IKK) and NF-kappaB
Chan et al., Biochem Biophys Res Commun 2005 : Tpl2/COT1 was shown to participate in CD40 signaling based on the ability of a catalytically inactive mutant to suppress CD40 mediated IkappaB kinase activation and induction of NFkappaB-responsive promoters, without affecting signaling by TNF