Gene interactions and pathways from curated databases and text-mining

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RGS4 — VEGFA

Text-mined interactions from Literome

Albig et al., Mol Biol Cell 2005 : Identification and characterization of regulator of G protein signaling 4 ( RGS4 ) as a novel inhibitor of tubulogenesis : RGS4 inhibits mitogen activated protein kinases and vascular endothelial growth factor signaling ... RGS4 had no effect on the phosphorylation of Smad1 and Smad2 by bone morphogenic protein-7 and transforming growth factor-beta, respectively, indicating that RGS4 selectively inhibits G protein and VEGF signaling in endothelial cells
Aguilar et al., Cancer Res 2012 (Cell Transformation, Viral) : Mechanistic investigations revealed that RGS4 reduced vGPCR enhanced cell proliferation, migration, VEGF expression, and Akt activation and suppressed tumor formation induced by vGPCR