◀ Back to MAPK8
MAPK8 — RBBP7
Pathways - manually collected, often from reviews:
-
OpenBEL Selventa BEL large corpus:
MAPK8
→
RBBP7
(increases, RBBP7 Activity)
Evidence: Furthermore, we have found that the c-Jun NH2-terminal kinase (JNK) pathway and GADD45, a growth arrest- and DNA damage-inducible gene, are constitutively activated in RbAp46-expressing cells.
Text-mined interactions from Literome
Wu et al., J Clin Invest 2002
(Myotonia Congenita) :
These findings suggest that the combined effects of class II
HDAC deficiency and p38
MAPK activation lead to potent upregulation of MEF2 transcriptional activity, which contributes to the long-term changes in gene expression and fiber-type transformation observed in myotonic skeletal muscles
Bode et al., Immunology 2007
:
In contrast,
HDAC inhibitors
had no effects on upstream nuclear factor-kappaB and
mitogen activated protein kinase activation