Gene interactions and pathways from curated databases and text-mining

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RPTOR — SETD2

Text-mined interactions from Literome

Horak et al., Proc Natl Acad Sci U S A 2010 (Cell Transformation, Viral...) : Surprisingly, however, HIF-1 up-regulation in REDD1 ( -/- ) cells is largely independent of mTORC1 activity
Cam et al., Mol Cell 2010 : mTORC1 signaling under hypoxic conditions is controlled by ATM dependent phosphorylation of HIF-1a
Kucejova et al., Mol Cancer Res 2011 (Carcinoma, Renal Cell) : REDD1 is upregulated by hypoxia-inducible factor (HIF)-1 , and forced REDD1 expression is sufficient to inhibit mTORC1
Finlay et al., Biochem Soc Trans 2013 : mTORC1 regulates glucose metabolism in CTLs through regulating the expression of the transcription factor HIF1a ( hypoxia-inducible factor 1a )