◀ Back to IFI27
E2F7 — IFI27
Text-mined interactions from Literome
Rivard et al., Am J Physiol 1999
:
In both cell types, expression of ras resulted in an increase of basal and serum stimulated
E2F dependent transcriptional activity and a reduction in
p27 ( Kip1 ) protein levels as well
Alexander et al., Mol Cell Biol 2001
:
In addition, the use of pRb proteins mutated in the pocket domain demonstrates that pRb upregulation of
p27 ( KIP1 ) and senescence induction do not
require the interaction of pRb with
E2F
Yuan et al., Cancer Res 2007
(Breast Neoplasms...) :
In sum, loss of
p27 activated AIB1,
E2F1 , Gab2, and Akt ; increased cell migration and invasion ; caused antiestrogen insensitivity ; and promoted metastasis of breast cancer cells