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DPH5 — REN

Text-mined interactions from Literome

Cadnapaphornchai et al., Proc Soc Exp Biol Med 1989 : In the present study, we examined the effects of adrenergic blockers in DPH stimulated renin release in five groups of anesthetized dogs ... In vehicle treated dogs, DPH at a dose of 0.18 mg/kg-min increased renin secretion rate (RSR) from 56 +/- 14 to 269 +/- 60 and returned to 84 +/- 30 ng of angiotensin (ANG) l/hr-min ( P less than 0.01, analysis of variance ) ... These data suggest that DPH stimulated renin release is mediated by beta 1 adrenoceptors since both beta 2 and alpha adrenoceptor antagonists have no effects on DPH stimulated renin release
Cadnapaphornchai et al., Am J Physiol 1984 : These data suggest that the stimulatory effect of DPH on renin release is mediated by or requires the presence of renal nerves
Migdal et al., J Pharmacol Exp Ther 1980 : Therefore, these studies were designed to elucidate the effect of DPH on renal function and renin release