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CCL20 — PLG
Text-mined interactions from Literome
Li et al., J Biomed Biotechnol 2012
(Atherosclerosis) :
The
plasmin induced
CCL20 expression was dependent on Akt- and ERK1/2 mediated phosphorylation of I?Ba on Ser32/36 and of p65 on Ser276, whereas p38 MAPK appeared to be dispensable ... Thus,
plasmin triggers release of the chemokine
CCL20 from dendritic cells, which might facilitate accumulation of CCR6 ( + ) immune cells in areas of plasmin generation such as inflamed tissues including atherosclerotic lesions
Li et al., Acta Biochim Biophys Sin (Shanghai) 2013
:
These results demonstrate that
plasmin triggers the expression of chemokine CCL20 messenger RNA and the release of
CCL20 protein in human monocyte derived macrophages, which critically depend on the proteolytic activity of plasmin and activation of p38 mitogen activated protein kinase and nuclear factor-kappaB signaling pathways