Gene interactions and pathways from curated databases and text-mining

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EDN1 — IL8

Text-mined interactions from Literome

Shiu et al., Eur J Haematol 2002 (Anemia, Sickle Cell...) : The presence of interleukin-1 in the perfusion system, as a model for inflammatory cytokine effects, enhanced the overall amounts of released prostacyclin but did not affect the production of endothelin-1
Stankevicius et al., Medicina (Kaunas) 2003 (Arteriosclerosis...) : The synthesis of endothelin-1 is induced by hypoxia, thrombin, interleukin-1 , transforming growth factor-beta1, vasopressin, and catecholamines
Kolb et al., Z Gesamte Inn Med 1991 (Anoxia...) : The synthesis of endothelin 1 in the endothelial cells is stimulated by adrenaline, noradrenaline, angiotensin II, arginine-vasopressin, thrombine, interleukin 1 and hypoxia
Kanse et al., Life Sci 1991 : Interleukin-1 beta, Interleukin-6 and interleukin-8 at various doses did not affect endothelin secretion
Virrey et al., Mol Cancer Ther 2010 (Brain Neoplasms...) : DMC caused no apparent effects on the secretion of vascular endothelial growth factor and interleukin-8 but inhibited the secretion of endothelin-1 in tumor associated EC
Mullol et al., Neuropeptides 1996 : Endothelin-1 induces GM-CSF, IL-6 and IL-8 but not G-CSF release from a human bronchial epithelial cell line ( BEAS-2B )
Hofman et al., Blood 1998 (Brain Ischemia...) : Endothelin-1 induces production of the neutrophil chemotactic factor interleukin-8 by human brain derived endothelial cells