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RPL23 — TP53
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Jin et al., Mol Cell Biol 2004
:
Inhibition of HDM2 and
activation of
p53 by
ribosomal protein L23
Lindström et al., PloS one 2010
(Brain Neoplasms...) :
In these settings,
RPL11 was critical for maintaining p53 protein stability but was not strictly
required for
p53 protein synthesis
Sun et al., J Biol Chem 2010
:
Perturbation of
60 S ribosomal biogenesis
results in ribosomal protein L5- and L11 dependent
p53 activation
Fumagalli et al., Genes Dev 2012
:
We show that depletion of RPS7 or
RPL23 , like depletion of other RPs, except for RPL11 and RPL5,
induces a
p53 response and that the effects of RPS7 and RPL23 on p53 induction reported earlier may be ascribed to inhibition of global translation
Zhang et al., Oncol Rep 2013
:
Previous studies have revealed that
ribosomal protein L23 (RPL23) inhibits MDM2 mediated
p53 degradation through direct binding to MDM2 ... In addition, ectopically expressed RPL23 was reported to interact with MDM2 in both the nucleus and cytoplasm, by which
RPL23 indirectly
inhibited MDM2-p53 binding