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AGTR1 — FGF2

Pathways - manually collected, often from reviews:

• NCI Pathway Database Angiopoietin receptor Tie2-mediated signaling: FGF2 (FGF2) → Angiotensin II/AGTR1 complex (AGTR1) (transcription, activates)
  Krikun et al., Biochem Biophys Res Commun 2000, Fujiyama et al., Circ Res 2001, Otani et al., Diabetes 2001
  Evidence: mutant phenotype, assay, reporter gene

Text-mined interactions from Literome

Gurantz et al., Circ Res 1999 : Ang II, transforming growth factor-beta(1), and basic fibroblast growth factor reduced AT(1) mRNA levels ( P < 0.02 )
Skaletz-Rorowski et al., Basic Res Cardiol 2004 : Angiotensin AT1 receptor upregulates expression of basic fibroblast growth factor , basic fibroblast growth factor receptor and coreceptor in human coronary smooth muscle cells ... AT1 receptor signaling which is characterized by phosphorylation of p42-mitogen activated protein kinase ( MAPK ) is involved in Ang II-induced bFGF , FGF-R1 and HSPG upregulation and DNA synthesis in human cSMC
Nickenig et al., Mol Pharmacol 1994 : The effects of epidermal growth factor, basic fibroblast growth factor , and platelet derived growth factor-BB on angiotensin type 1 (AT1) receptor gene expression were examined in rat thoracic aorta vascular smooth muscle cells ( VSMC ) in culture
Langlois et al., Endocrinology 1994 : Insulin, Insulin-like growth factor and basic Fibroblast growth factor increased AT1 receptors ( mRNA and binding sites ) as well as the alpha subunit of Gq ( mRNA and protein ) and G11 ( protein )