◀ Back to AKT3

AKT3 — PEA15

Text-mined interactions from Literome

Trencia et al., Mol Cell Biol 2003 (Glioma) : In intact 293 cells, Akt also induced phosphorylation of PED/PEA-15 at Ser ( 116 ) ... In part, Akt survival signaling may be mediated by PED/PEA-15
Stassi et al., Cancer Res 2005 (Breast Neoplasms) : We show that human breast cancer cells express high levels of PED and that AKT activity regulates PED protein levels ... Thus, AKT dependent increase of PED expression levels represents a key molecular mechanism for chemoresistance in breast cancer
Gervais et al., Mol Biol Cell 2006 : We report that Akt binds to PEA-15 and that Akt activation leads to PEA-15 stabilization, independently of PEA-15 interaction with ERK1/2
Hayashi et al., Cell Death Differ 2012 : Furthermore, we show that Hsp27 regulation of PEA-15 activity occurs in an Akt dependent manner