Gene interactions and pathways from curated databases and text-mining

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C5AR1 — EPHB2

Text-mined interactions from Literome

Zhang et al., Cell Mol Immunol 2007 : Our results showed stable expression of the C5aR in Molt-4 cell line and their interaction with human C5a induced ERK1/2 phosphorylation, Ca++ influx
Karsten et al., Nat Med 2012 (Autoimmune Diseases) : This pathway blocks C5aR mediated ERK1/2 phosphorylation, C5a effector functions in vitro and C5a dependent inflammatory responses in vivo, including peritonitis and skin blisters in experimental epidermolysis bullosa acquisita