Wang et al., Mol Carcinog 2009
(Carcinoma, Transitional Cell...) :
We further determined that recombinant epiregulin increased both cell proliferation and Erk phosphorylation in UMUC-3 bladder cancer cells
Hu et al., Oral Oncol 2009
(Carcinoma, Adenoid Cystic...) :
Furthermore, epiregulin not only induced activation of both ERK1/2 and Akt, but also expression of COX-2
Neufert et al., J Clin Invest 2013
(Colitis...) :
Additionally, we demonstrated that fibroblast derived EREG requires ERK activation to induce proliferation of intestinal epithelial cells ( IEC ) and tumor development in vivo