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IRF6 — TFRC
Text-mined interactions from Literome
Reis et al., J Neurosci Res 2006
(Neuroblastoma) :
The
LPS down-regulatory
effect on
TfR protein expression is abolished by the NADPH oxidase inhibitor diphenyliodonium ( DPI ) but is not affected by the free radical scavenger N-acetyl-L-cysteine (NAC) or the iNOS inhibitor aminoguanidine ( AG )
Tacchini et al., J Biol Chem 2008
(Inflammation) :
Activation of an anti-inflammatory pathway by pre-exposure to the adenosine A(2A) receptor agonist CGS21680 prevented the inducing
effect of
LPS/IFNgamma on HIF-1 and
TfR1 expression by inhibiting NF-kappaB activity, whereas treatment with CGS21680 alone increased HIF-1 mediated TfR1 expression by means of an NF-kappaB independent signaling pathway
Henderson et al., J Biol Chem 1993
:
IRF controls expression of ferritin and
transferrin receptor post-transcriptionally via specific binding to stem-loop iron-responsive elements ( IREs ) located in the untranslated regions of the respective mRNAs