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ALB — CASP4
Text-mined interactions from Literome
Murayama et al., J Cell Sci 2004
(Neoplasms) :
For the possible mechanism of ALB6 induced apoptosis,
ALB6 activated the c-Jun NH2-terminal kinase/stress activated protein kinase ( JNK/SAPK ) and p38 mitogen-activated-protein kinase ( MAPK ) within 5-15 minutes, as well as
caspase-3 within 24-48 hours ... It is noteworthy that
ALB6 induced tyrosine phosphorylation of the p46 Shc isoform specifically and that the overexpression of its dominant negative form completely suppressed the ALB6 induced activation of JNK/SAPK, p38 MAPK and
caspase-3 , resulting in the inhibition of apoptotic cell death
Higuchi et al., Curr Eye Res 2007
(Disease Models, Animal...) :
Apoptosis suppression assay using cell lines revealed that
caspase-3 activation induced by serum deprivation and DNA fragmentation induced by addition of apoptosis inducers were dose-dependently
suppressed by
albumin
Brezniceanu et al., J Am Soc Nephrol 2010
(Diabetic Nephropathies...) :
In vitro,
albumin stimulated activity of both caspase-12 and
caspase-3 as well as expression of caspase-12 and CCAT/enhancer binding protein homologous protein in a human proximal tubule cell line ( HK-2 )