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NUP43 — PGR
Text-mined interactions from Literome
Qiu et al., J Steroid Biochem Mol Biol 2003
:
Bidirectional cross-talk between these two pathways is well documented ; progestins increase the expression of type I growth factor receptors that couple to MAPK activation, and in turn, activation of
p42 and p44 MAPKs
increases ligand dependent
progesterone receptor (PR) transcriptional activity, and parodoxically, augments PR downregulation
Pierson-Mullany et al., Breast Dis 2003
:
Activation of
p42 and p44 MAPKs
increases progesterone receptor (PR) transcriptional activity in the presence of progestins, and triggers their rapid down-regulation by the ubiquitin-proteasome pathway