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ARF6 — SRC

Pathways - manually collected, often from reviews:

• NCI Pathway Database Arf6 signaling events: Src (SRC) → ARF6/GDP complex (ARF6) (modification, activates) Palacios et al., EMBO J 2001
  Evidence: mutant phenotype
• NCI Pathway Database Posttranslational regulation of adherens junction stability and dissassembly: Src (SRC) → ARF6/GDP complex (ARF6) (modification, activates) Palacios et al., EMBO J 2001
  Evidence: mutant phenotype

Text-mined interactions from Literome

Heckel et al., Proc Natl Acad Sci U S A 2009 (Bone Resorption) : Src dependent repression of ARF6 is required to maintain podosome-rich sealing zones in bone digesting osteoclasts
Morgan et al., Dev Cell 2013 : Src phosphorylates syndecan-4 and, by driving syntenin binding, leads to suppression of Arf6 activity and recycling of aVß3 to the plasma membrane at the expense of a5ß1