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CHUK — PCNA
Text-mined interactions from Literome
Wang et al., Mol Cell Biol 2001
:
Cyclin D1 repression was
independent of
IKK , as prostaglandins (PGs) which bound PPARgamma but lacked the IKK interactive cyclopentone ring carbonyl group repressed cyclin D1
Song et al., Biochim Biophys Acta 2010
(MAP Kinase Signaling System) :
Notably,
IKKa dependent
Cyclin D1 regulation is unrelated to IKKbeta/NF-kappaB activity ... We further show that
IKKalpha dependent downregulation of
Cyclin D1 expression in the UVB response results from the reduction of ERK1/2 dependent Cyclin D1 transcription coupled with an increase of p38 kinase dependent Cyclin D1 proteolysis