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ARSA — NOS2

Text-mined interactions from Literome

De La Cruz et al., J Neurosci Res 2004 (Disease Models, Animal...) : In brain tissue subjected to hypoxia, ASA reduced oxidative stress and iNOS activity ( all increased by hypoxia ), but only when used at higher concentrations
Konturek et al., J Physiol Pharmacol 2006 (Helicobacter Infections) : Furthermore, in comparison to plain ASA, ASA-VitC caused stronger inhibition of cNOS and increase in iNOS expression in the gastric mucosa ... We conclude that ASA-VitC in comparison with ASA induces less gastric mucosal damage and this protective effect may be due to its inhibitory effect on iNOS expression
Nandi et al., Dig Dis Sci 2008 (Disease Models, Animal...) : We evaluated indomethacin induced enteropathy in rats, in relation to the expression of the inducible isoform of NO synthase (iNOS) using aminosalicylic acid ( 5-ASA ), its isomer 4-ASA ( 10 or 50 mg/kg/day, po ), and dexamethasone, an iNOS transcription inhibitor ( 3 mg/kg/day, sc )
Linard et al., J Pharmacol Exp Ther 2008 (Colitis...) : Therefore, 5-ASA prevents irradiation induced inflammatory processes as well as expression of tumor necrosis factor alpha, monocyte chemotactic protein-1, inducible nitric-oxide synthase , and macrophage infiltration